Bay ÖF, Hayes KS, Schwartz JM, Grencis RK, Roberts IS (2023). A genome-scale metabolic model of parasitic whipworm. Nature Communications 14: 6937.
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Mpabanzi L, Wainwright J, Boonen B, van Eijk H, Dhar D, Karssemeijer E, Dejong CHC, Jalan R, Schwartz JM, Olde Damink SWM, Soons Z (2022). Fluxomics reveals cellular and molecular basis of increased renal ammoniagenesis. npj Systems Biology and Applications 8: 49.
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Watson J, Ferguson HR, Brady RM, Ferguson J, Fullwood P, Mo H, Bexley KH, Knight D, Howell G, Schwartz JM, Smith MP, Francavilla C (2022). Spatially resolved phosphoproteomics reveals fibroblast growth factor receptor recycling-driven regulation of autophagy and survival. Nature Communications 13: 6589.
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Tchicaya-Bouanga J, Hung YJ, Schwartz JM, Yoon DJY, Chotard E, Marty C, Odri GA, de Pinieux G, Cohen-Solal M, Modrowski D (2022). A calpain-6/YAP axis in sarcoma stem cells that drives the outgrowth of tumors and metastases. Cell Death and Disease 13: 819.
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Watson J, Smith M, Francavilla C, Schwartz JM (2022). SubcellulaRVis: a web-based tool to simplify and visualise subcellular compartment enrichment. Nucleic Acids Research 50(W1): W718-25.
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Mo H, Breitling R, Francavilla C, Schwartz JM (2022). Data integration and mechanistic modelling for breast cancer biology: Current state and future directions. Current Opinion in Endocrine and Metabolic Research 24: 100350.
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Saunders HA, Calzadilla PI, Schwartz JM, Johnson GN (2022). Cytosolic fumarase acts as a metabolic fail-safe for both high and low temperature acclimation of Arabidopsis thaliana. Journal of Experimental Botany 73: 2112-24.
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Saunders HA, Schwartz JM (2021). COVID-19 vaccination strategies depend on the underlying network of social interactions. Scientific Reports 11: 24051.
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Timouma S, Balarezo-Cisneros LN, Pinto J, De La Cerda R, Bond U, Schwartz JM, Delneri D (2021). Transcriptional profile of the industrial hybrid Saccharomyces pastorianus reveals temperature-dependent allele expression bias and preferential orthologous protein assemblies. Molecular Biology and Evolution 38: 5437-52.
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Zarka M, Etienne F, Bourmaud M, Szondi D, Schwartz JM, Kampmann K, Helary C, Rannou F, Haÿ E, Cohen-Solal M (2021). Mechanical loading activates the YAP/TAZ pathway and chemokine expression in the MLO-Y4 osteocyte-like cell line. Laboratory Investigation 101: 1597-1604.
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Watson J, Schwartz JM, Francavilla C (2021). Using multilayer heterogeneous networks to infer functions of phosphorylated sites. Journal of Proteome Research 20: 3532-48.
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Gjindali A, Herrmann HA, Schwartz JM, Johnson GN, Calzadilla PI (2021). A holistic approach to study photosynthetic acclimation responses of plants to fluctuating light. Frontiers in Plant Science 12: 668512.
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Hetmanski JH, Jones MC, Chunara F, Schwartz JM, Caswell PT (2021). Combinatorial mathematical modelling approaches to interrogate rear retraction dynamics in 3D cell migration. PLOS Computational Biology 17: e1008213.
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Westermann LM, Baranowsky A, Di Lorenzo G, Danyukova T, Soul J, Schwartz JM, Hendrickx G, Amling M, Rose-John S, Garbers C, Schinke T, Pohl S (2021). Transgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II mice. Scientific Reports 11: 3556.
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Yap CF, Garcia-Albornoz M, Jarnuczak AF, Hubbard SJ, Schwartz JM (2021). Model parameterization with quantitative proteomics: case study with trehalose metabolism in Saccharomyces cerevisiae. Processes 9: 139.
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Herrmann HA, Schwartz JM (2020). Why COVID-19 models should incorporate the network of social interactions. Physical Biology 17: 065008.
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Timouma S, Schwartz JM, Delneri D (2020). HybridMine: a pipeline for allele inheritance and gene copy number prediction in hybrid genomes and its applications to industrial yeasts. Microorganisms 8: 1554.
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Medupin C, Bannister C, Schwartz JM (2020). Exploring the interactions of physical, chemical and biological variables of an urban river using network analysis. Water 12: 2578.
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Herrmann HA, Schwartz JM, Johnson GN (2020). From empirical to theoretical models of light response curves - linking photosynthetic and metabolic acclimation. Photosynthesis Research 145: 5-14.
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Hetmanski JHR, de Belly H, Busnelli I, Waring T, Nair RV, Sokleva V, Dobre O, Cameron A, Gauthier N, Lamaze C, Swift J, Del Campo A, Starborg T, Zech T, Goetz JG, Paluch EK, Schwartz JM, Caswell PT (2019). Membrane tension orchestrates rear retraction in matrix-directed cell migration. Developmental Cell 51: 460-75.
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Herrmann HA, Dyson BC, Vass L, Johnson GN, Schwartz JM (2019). Flux sampling is a powerful tool to study metabolism under changing environmental conditions. npj Systems Biology and Applications 5: 32.
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Buiga P, Elson A, Tabernero L, Schwartz JM (2019). Kinetic modeling of DUSP regulation in Herceptin-resistant HER2-positive breast cancer. Genes 10: 568.
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Soul J, Hardingham T, Boot-Handford R, Schwartz JM (2019). SkeletalVis: an exploration and meta-analysis data portal of cross-species skeletal transcriptomics data. Bioinformatics 35: 2283-90.
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Piróg KA, Dennis EP, Hartley CL, Jackson RM, Soul J, Schwartz JM, Bateman JF, Boot-Handford RP, Briggs MD (2019). XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease. PLOS Genetics 15: e1008215.
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Schwartz JM, Otokuni H, Akutsu T, Nacher JC (2019). Probabilistic controllability approach to metabolic fluxes in normal and cancer tissues. Nature Communications 10: 2725.
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Herrmann HA, Schwartz JM, Johnson GN (2019). Metabolic acclimation - a key to enhancing photosynthesis in changing environments? Journal of Experimental Botany 70: 3043-56.
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Paganini C, Monti L, Costantini R, Besio R, Lecci S, Biggiogera M, Tian K, Schwartz JM, Huber C, Cormier-Daire V, Gibson BG, Pirog KA, Forlino A, Rossi A (2019). Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification. Matrix Biology 81: 70-90.
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Buiga P, Elson A, Tabernero L, Schwartz JM (2019). Modelling the role of dual specificity phosphatases in Herceptin resistant breast cancer cell lines. Computational Biology and Chemistry 80: 138-46.
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Ravindran V, Nacher JC, Akutsu T, Ishitsuka M, Osadcenco A, Sunitha V, Bagler G, Schwartz JM, Robertson DL (2019). Network controllability analysis of intracellular signalling reveals viruses are actively controlling molecular systems. Scientific Reports 9: 2066.
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Méndez-Leyva AB, Guo J, Mudd EA, Wong J, Schwartz JM, Day A (2019). The chloroplast genome of the marine microalga Tisochrysis lutea. Mitochondrial DNA Part B 4: 253-5.
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Schwartz JM, Soons Z (2019). Metabolic models. In: Encyclopedia of Bioinformatics and Computational Biology, Elsevier, ed. S. Ranganathan, M. Gribskov, K. Nakai, C. Schönbach, 2: 438-44.
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Buiga P, Soul J, Schwartz JM (2018). A meta-analysis portal for human breast cancer transcriptomics data: BreastCancerVis. 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM): 260-264.
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Miraee-Nedjad S, Sims PFG, Schwartz JM, Doig AJ (2018). Effect of IAPP on the proteome of cultured Rin-5F cells. BMC Biochemistry 19: 9.
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Stoney RA, Schwartz JM, Robertson DL, Nenadic G (2018). Using set theory to reduce redundancy in pathway sets. BMC Bioinformatics 19: 386.
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Tian K, Bakker E, Hussain M, Guazzelli A, Alhebshi H, Meysami P, Demonacos C, Schwartz JM, Mutti L, KrsticDemonacos M (2018). p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification. Journal of Translational Medicine 16: 282.
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Hetmanski JHR, Schwartz JM, Caswell PT (2018). Modeling Rho GTPase dynamics using Boolean logic. In: Rho GTPases: Methods and Protocols, Humana Press, ed. F. Rivero, Methods in Molecular Biology 1821: 37-46.
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Stoney R, Robertson DL, Nenadic G, Schwartz JM (2018). Mapping biological process relationships and disease perturbations within a pathway network. npj Systems Biology and Applications 4: 22.
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Buiga P, Elson A, Tabernero L, Schwartz JM (2018). Regulation of dual specificity phosphatases in breast cancer during initial treatment with Herceptin: a Boolean model analysis. BMC Systems Biology 12(Suppl 1): 11.
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Hetmanski JHR, Schwartz JM, Caswell PT (2018). Rationalizing Rac1 and RhoA GTPase signaling: A mathematical approach. Small GTPases 9: 224-9.
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Soul J, Dunn SL, Anand S, Serracino-Inglott F, Schwartz JM, Boot-Handford R, Hardingham T (2018). Stratification of knee osteoarthritis: two major patient subgroups identified by genome-wide expression analysis of articular cartilage. Annals of the Rheumatic Diseases 77: 423-30.
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Bakker E, Tian K, Mutti L, Demonacos C, Schwartz JM, Krstic-Demonacos M (2017). Insight into glucocorticoid receptor signalling through interactome model analysis. PLOS Computational Biology 13: e1005825.
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Chapman S, Trindade dos Santos M, Johnson G, Kritz M, Schwartz JM (2017). Cyclic decomposition explains a photosynthetic down regulation for Chlamydomonas reinhardtii. Biosystems 162: 119-27.
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Qattan MY, Bakker EY, Rajendran R, Chen DWC, Saha V, Liu J, Zeef L, Schwartz JM, Mutti L, Demonacos C, Krstic-Demonacos M (2017). Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia. PLOS One 12: e0178606.
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Gioia R, Tonelli F, Ceppi I, Biggiogera M, Leikin S, Fisher S, Tenedini E, Yorgan TA, Schinke T, Tian K, Schwartz JM, Forte F, Wagener R, Villani S, Rossi A, Forlino A (2017). The chaperone activity of 4PBA ameliorates the skeletal phenotype of Chihuahua, a zebrafish model for dominant osteogenesis imperfecta. Human Molecular Genetics 26: 2897-2911.
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Strangward P, Haley MJ, Shaw TN, Schwartz JM, Greig R, Mironov A, Brian de Souza J, Cruickshank SM, Craig AG, Milner DA, Allan SM, Couper KN (2017). A quantitative brain map of experimental cerebral malaria pathology. PLOS Pathogens 13: e1006267.
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Hetmanski JH, Schwartz JM, Caswell PT (2016). Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion. Biochemical Society Transactions 44: 1695-1700.
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Soul J, Dunn SL, Hardingham TE, Boot-Handford RP, Schwartz JM (2016). PhenomeScape: a Cytoscape app to identify differentially regulated sub-networks using known disease associations. Bioinformatics 32: 3847-9.
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Dunn SL, Soul J, Anand S, Schwartz JM, Boot-Handford RP, Hardingham TE (2016). Gene expression changes in damaged osteoarthritic cartilage identify a signature of non-chondrogenic and mechanical responses. Osteoarthritis and Cartilage 24: 1431-40.
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Hetmanski JHR, Zindy E, Schwartz JM, Caswell PT (2016). A MAPK-driven feedback loop suppresses Rac activity to promote RhoA-driven cancer cell invasion. PLOS Computational Biology 12: e1004909.
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Stoney R, Ames R, Nenadic G, Robertson DL, Schwartz JM (2015). Disentangling the multigenic and pleiotropic nature of molecular function. BMC Systems Biology 9(Suppl 6): S3.
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Wu C, Schwartz JM, Brabant G, Peng SL, Nenadic G (2015). Constructing a molecular interaction network for thyroid cancer via large-scale text mining of gene and pathway events. BMC Systems Biology 9(Suppl 6): S5.
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Schwartz JM, Barber M, Soons Z (2015). Metabolic flux prediction in cancer cells with altered substrate uptake. Biochem Soc Trans 43: 1177-81.
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Hussain M, Tian K, Mutti L, Krstic-Demonacos M, Schwartz JM (2015). The expanded p53 interactome as a predictive model for cancer therapy. Genomics and Computational Biology 1: e20.
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Jarnuczak AF, Eyers CE, Schwartz JM, Grant CM, Hubbard SJ (2015). Quantitative proteomics and network analysis of SSA1 and SSB1 deletion mutants reveals robustness of chaperone HSP70 network in Saccharomyces cerevisiae. Proteomics 15: 3126-39.
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Chapman SP, Paget CM, Johnson GN, Schwartz JM (2015). Flux balance analysis reveals acetate metabolism modulates cyclic electron flow and alternative glycolytic pathways in Chlamydomonas reinhardtii. Frontiers in Plant Science 6: 474.
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Oyeyemi OJ, Davies O, Robertson DL, Schwartz JM (2015). A logical model of HIV-1 interactions with the T-cell activation signalling pathway. Bioinformatics 31: 1075-83.
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Soul J, Hardingham TE, Boot-Handford RP, Schwartz JM (2015). PhenomeExpress: A refined network analysis of expression datasets by inclusion of known disease phenotypes. Scientific Reports 5: 8117.
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Wu C, Schwartz JM, Brabant G, Nenadic G (2014). Molecular profiling of thyroid cancer subtypes using large-scale text-mining. BMC Medical Genomics 7(Suppl 3): S3.
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Paget CM, Schwartz JM, Delneri D (2014). Environmental systems biology of cold-tolerant phenotype in Saccharomyces species adapted to grow at different temperatures. Molecular Ecology 23: 5241-57.
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Schwartz JM, Taylor PN (2014). In silico prediction of elementary mode fluxes. Proceedings International Work-Conference on Bioinformatics and Biomedical Engineering (IWBBIO 2014) 1: 183-91.
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Hussain M, Stutchbury B, Tian K, Atalay R, Schwartz JM, Krstic-Demonacos M (2014). Applications of p53 interactome analysis to personalised drug discovery. Proceedings International Work-Conference on Bioinformatics and Biomedical Engineering (IWBBIO 2014) 1: 192-203.
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Nacher JC, Keith B, Schwartz JM (2014). Network medicine analysis of chondrocyte proteins towards new treatments of osteoarthritis. Proceedings of the Royal Society B 281: 20132907.
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Wu C, Schwartz JM, Nenadic G (2013). PathNER: A tool for systematic identification of biological pathway mentions in the literature. BMC Systems Biology 7(Suppl 3): S2.
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Tian K, Rajendran R, Doddananjaiah M, Krstic-Demonacos M, Schwartz JM (2013). Dynamics of DNA damage induced pathways to cancer. PLOS One 8: e72303.
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Chen DWC, Saha V, Liu JZ, Schwartz JM, Krstic-Demonacos M (2013). Erg and AP-1 as determinants of glucocorticoid response in acute lymphoblastic leukemia. Oncogene 32: 3039-48.
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Schwartz JM, Nacher JC (2013). Systems pharmacology, drug disease interactions. In: Encyclopedia of Systems Biology, Springer, ed. W. Dubitzky, O. Wolkenhauer, K.H. Cho, H. Yokota: 2103-6.
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Nacher JC, Schwartz JM (2013). Systems pharmacology, drug-target networks. In: Encyclopedia of Systems Biology, Springer, ed. W. Dubitzky, O. Wolkenhauer, K.H. Cho, H. Yokota: 2106-8.
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Chen DWC, Krstic-Demonacos M, Schwartz JM (2012). Modeling the mechanism of GR/c-Jun/Erg crosstalk in apoptosis of acute lymphoblastic leukemia. Frontiers in Physiology 3: 410.
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Williamson T, Adiamah DA, Schwartz JM, Stateva L (2012). Exploring the genetic control of glycolytic oscillations in Saccharomyces cerevisiae. BMC Systems Biology 6: 108.
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Adiamah DA, Schwartz JM (2012). Construction of a genome-scale kinetic model of Mycobacterium tuberculosis using generic rate equations. Metabolites 2: 382-97.
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Tseng YY, Hunt SM, Heintzen C, Crosthwaite SK, Schwartz JM (2012). Comprehensive modelling of the Neurospora circadian clock and its temperature compensation. PLOS Computational Biology 8: e1002437.
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Nacher JC, Schwartz JM (2012). Modularity in protein complex and drug interactions reveals new polypharmacological properties. PLOS One 7: e30028.
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Schwartz JM, Gaugain C (2011). Genome-scale integrative data analysis and modeling of dynamic processes in yeast. In: Yeast Systems Biology, Springer, ed. J.I. Castrillo, S.G. Oliver, Methods in Molecular Biology 759: 427-43.
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Chen DWC, Lynch JT, Demonacos C, Krstic-Demonacos M, Schwartz JM (2010). Quantitative analysis and modeling of glucocorticoid-controlled gene expression. Pharmacogenomics 11: 1545-60.
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Radrich K, Tsuruoka Y, Dobson P, Gevorgyan A, Swainston N, Baart G, Schwartz JM (2010). Integration of metabolic databases for the reconstruction of genome-scale metabolic networks. BMC Systems Biology 4: 114.
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Adiamah DA, Handl J, Schwartz JM (2010). Generic dynamic modeling of metabolic systems. Proceedings Dynamic Days South America 2010: International Conference on Chaos and Nonlinear Dynamics.
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Kritz MV, Trindade dos Santos M, Urrutia S, Schwartz JM (2010). Organising metabolic networks: cycles in flux distributions. Journal of Theoretical Biology 265: 250-60.
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Adiamah DA, Handl J, Schwartz JM (2010). Streamlining the construction of large-scale dynamic models using generic kinetic equations. Bioinformatics 26: 1324-31.
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Williamson T, Schwartz JM, Kell DB, Stateva L (2009). Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae. BMC Systems Biology 3: 70.
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Schwartz JM, Nacher JC (2009). Local and global modes of drug action in biochemical networks. BMC Chemical Biology 9: 4.
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Nacher JC, Schwartz JM (2008). A global view of drug-therapy interactions. BMC Pharmacology 8: 5.
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Schwartz JM, Gaugain C, Nacher JC, de Daruvar A, Kanehisa M (2007). Observing metabolic functions at the genome scale. Genome Biology 8: R123.
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Schwartz JM, Laurendeau D, Denninger M, Rancourt D, Simo C (2007). Modeling techniques for liver tissue properties and their application in surgical treatment of liver cancer. In: Biomechanical Systems Technology, World Scientific, ed. C.T. Leondes, 4: 45-81.
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Nacher JC, Schwartz JM, Kanehisa M, Akutsu T (2006). Identification of metabolic units induced by environmental signals. Bioinformatics 22: e375-83.
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Schwartz JM, Kanehisa M (2006). Quantitative elementary mode analysis of metabolic pathways: the example of yeast glycolysis. BMC Bioinformatics 7: 186.
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Schwartz JM, Kanehisa M (2005). A quadratic programming approach for decomposing steady-state metabolic flux distributions onto elementary modes. Bioinformatics 21: ii204-5.
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Schwartz JM, Denninger M, Rancourt D, Moisan C, Laurendeau D (2005). Modelling liver tissue properties using a non-linear visco-elastic model for surgery simulation. Medical Image Analysis 9: 103-12.
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Schwartz JM, Kanehisa M (2004). Decomposition of kinetically feasible metabolic flux distributions onto elementary modes. Genome Informatics 15(2): P069.
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Schwartz JM, Kanehisa M (2004). Combining kinetics and network-based pathway analysis. Genome Informatics 15(1): 59-60.
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Schwartz JM, Laurendeau D, Denninger M, Rancourt D (2004). Geometrically and physically non-linear models for soft tissue simulation. Proceedings 6th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE 2004): 48C.
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Mokhtari M, Bernier F, Lemieux F, Martel H, Schwartz JM, Laurendeau D, Branzan-Albu A (2004). Virtual environment and sensori-motor activities: haptic, audition and olfaction. Proceedings International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision (WSCG 2004): 109-12.
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Branzan Albu A, Schwartz JM, Laurendeau D, Moisan C (2003). Integrating geometric and biomechanical models of a liver tumour for cryosurgery simulation. Lecture Notes in Computer Science 2673: 121-31.
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Schwartz JM, Denninger M, Rancourt D, Moisan C, Laurendeau D (2002). Modelling liver tissue properties using a non-linear viscoelastic model for surgery simulation. ESAIM Proceedings 12: 146-53.
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Schwartz JM, Langelier È, Moisan C, Laurendeau D (2001). Non-linear soft tissue deformations for the simulation of percutaneous surgeries. Lecture Notes in Computer Science 2208: 1271-2.
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Schneider N, Schwartz JM, Köhler J, Becker M, Schwarz H, Gerisch G (2000). Golvesin-GFP fusions as distinct markers for Golgi and post-Golgi vesicles in Dictyostelium cells. Biology of the Cell 92: 495-511.
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Koonce MP, Köhler J, Neujahr R, Schwartz JM, Tikhonenko I, Gerisch G (1999). Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position. EMBO Journal 18: 6786-92.
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Gabriel D, Hacker U, Köhler J, Müller-Taubenberger A, Schwartz JM, Westphal M, Gerisch G (1999). The contractile vacuole network of Dictyostelium as a distinct organelle: its dynamics visualized by a GFP marker protein. Journal of Cell Science 112: 3995-4005.
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Weber I, Gerisch G, Heizer C, Murphy J, Badelt K, Stock A, Schwartz JM, Faix J (1999). Cytokinesis mediated through the recruitment of cortexillins into the cleavage furrow. EMBO Journal 18: 586-94.
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Peracino B, Borleis J, Jin T, Westphal M, Schwartz JM, Wu L, Bracco E, Gerisch G, Devreotes P, Bozzaro S (1998). G protein beta subunit-null mutants are impaired in phagocytosis and chemotaxis due to inappropriate regulation of the actin cytoskeleton. Journal of Cell Biology 141: 1529-37.
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Neujahr R, Albrecht R, Köhler J, Matzner M, Schwartz JM, Westphal M, Gerisch G (1998). Microtubule-mediated centrosome motility and the positioning of cleavage furrows in multinucleate myosin II-null cells. Journal of Cell Science 111: 1227-40.
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Neujahr R, Heizer C, Albrecht R, Ecke M, Schwartz JM, Weber I, Gerisch G (1997). Three-dimensional patterns and redistribution of myosin II and actin in mitotic Dictyostelium cells. Journal of Cell Biology 139: 1793-804.
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Westphal M, Jungbluth A, Heidecker M, Mühlbauer B, Heizer C, Schwartz JM, Marriott G, Gerisch G (1997). Microfilament dynamics during cell movement and chemotaxis monitored using a GFP-actin fusion protein. Current Biology 7: 176-83.
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