WORKLIST ENTRIES (1):

EAGCHANLFMLY View alignment     EAG/ELK/ERG potassium channel family signature
 Type of fingerprint: COMPOUND with 10 elements
Links:
   PRINTS; PR00169 KCHANNEL; PR01464 EAGCHANNEL; PR01465 ELKCHANNEL
   PRINTS; PR01470 ERGCHANNEL

 Creation date 01-DEC-2000

   1. MILLER, C.
   An overview of the potassium channel family.
   GENOME BIOL. 1(4) 1-5 (2000).

   2. ASHCROFT, F.M.
   Voltage-gated K+ channels
   IN ION CHANNELS AND DISEASE, ACADEMIC PRESS, 2000, PP.97-123.

   3. LITTLETON, J.T. AND GANETZKY, B.
   Ion channels and synaptic organisation: analysis of the Drosophila genome.
   NEURON 26 35-43 (2000).

   Potassium ion (K+) channels are a structurally diverse group of proteins
   that facilitate the flow of K+ ions across cell membranes. They are
   ubiquitous, being present in virtually all cell types. Activation of K+
   channels tends to hyperpolarise cells, reducing the membrane's electrical
   resistance, dampening nervous activity. In eukaryotic cells, K+ channels
   are involved in neural signalling and generation of the cardiac rhythm, and
   act as effectors in signal transduction pathways involving G protein-
   coupled receptors (GPCRs). In prokaryotic cells, they play a role in the
   maintenance of ionic homeostasis [1].
  
   Structurally, EAG channels belong to the subfamily of K+ channels whose
   subunits contain 6 transmembrane (TM) domains: these are the voltage-gated
   K+ channels, the KCNQ channels, the EAG-like K+ channels and 3 kinds of
   Ca2+-activated K+ channel (BK, IK and SK) [2]. All K+ channels share a
   characteristic sequence feature: a TMxTVGYG motif that resides between the
   2 C-terminal membrane-spanning helices, and forms the K+-selective pore 
   domain [1]. However, unlike other families within this structural class,
   EAG channels possess a cyclic nucleotide binding domain within their 
   putative intracellular C-termini.
  
   The first EAG K+ channel was identified in Drosophila, following a screen 
   for mutations giving rise to behavioural abnormalities. Disruption of the
   Eag gene caused an ether-induced, leg-shaking behaviour. Subsequent studies
   have revealed a conserved multi-gene family of EAG-like K+ channels, which
   are present in Homo sapiens and many other species. Based on the varying
   functional properties of the channels, the family has been divided into
   3 subfamilies: EAG, ELK and ERG. Interestingly, C.elegans appears to lack
   the ELK type [3].
  
   EAGCHANLFMLY is a 10-element fingerprint that provides a signature for the
   EAG/ELK/ERG K+ channel family. The fingerprint was derived from an initial
   alignment of 10 sequences: the motifs were drawn from conserved regions
   spanning the full alignment length, focusing on those sections that 
   characterise the EAG/ELK/ERG channels but distinguish them from other 
   members of the K+ channel superfamily; motifs 1 and 2 span putative TM 
   domain 2; motifs 3 and 4 encompass TM domain 3; motif 5 spans TM domain 4; 
   motifs 6-9 encompass TM domain 5; and motif 10 encodes TM domain 
   6. Three iterations on SPTR39_14f were required to reach convergence, at
   which point a true set comprising 32 sequences was identified.

  SUMMARY INFORMATION
     32 codes involving 10 elements
      0 codes involving  9 elements
      0 codes involving  8 elements
      0 codes involving  7 elements
      0 codes involving  6 elements
      0 codes involving  5 elements
      0 codes involving  4 elements
      0 codes involving  3 elements
      0 codes involving  2 elements

   COMPOSITE FINGERPRINT INDEX
  
   10|  32   32   32   32   32   32   32   32   32   32  
    9|   0    0    0    0    0    0    0    0    0    0  
    8|   0    0    0    0    0    0    0    0    0    0  
    7|   0    0    0    0    0    0    0    0    0    0  
    6|   0    0    0    0    0    0    0    0    0    0  
    5|   0    0    0    0    0    0    0    0    0    0  
    4|   0    0    0    0    0    0    0    0    0    0  
    3|   0    0    0    0    0    0    0    0    0    0  
    2|   0    0    0    0    0    0    0    0    0    0  
   --+---------------------------------------------------
     |   1    2    3    4    5    6    7    8    9   10  

True positives..
 O35989         O35221         O35220         O35219         
 HERG_HUMAN     O19119         O08962         O54853         
 Q9TSZ3         O54852         O02497         Q18325         
 O18965         O18966         O76035         O95259         
 Q60603         Q63472         O88877         Q9VXZ6         
 CIKE_DROME     Q9QXT2         Q9V899         Q23974         
 Q9R1T9         O89048         Q9UQ05         O89047         
 Q9UQ06         Q9WVJ0         O44164         Q9XYX7         


  PROTEIN TITLES
   O35989           ERG B K+ CHANNEL ISOFORM - Mus musculus (Mouse).
   O35221           MERG1A (MERG1A') - Mus musculus (Mouse).
   O35220           LONG (ELECTOCARDIOGRAPHIC) QT SYNDROME 2 (MERG1B) - Mus musc
   O35219           LONG (ELECTOCARDIOGRAPHIC) QT SYNDROME 2 (ETHER-A-GO-GO-RELA
   HERG_HUMAN       VOLTAGE-GATED POTASSIUM CHANNEL HERG (POTASSIUM CHANNEL, VOL
   O19119           VENTRICULAR ERG K+ CHANNEL SUBUNIT - Oryctolagus cuniculus (
   O08962           R-ERG - Rattus norvegicus (Rat).
   O54853           POTASSIUM CHANNEL - Rattus norvegicus (Rat).
   Q9TSZ3           POTASSIUM CHANNEL - Canis familiaris (Dog).
   O54852           POTASSIUM CHANNEL - Rattus norvegicus (Rat).
   O02497           SEI PROTEIN - Drosophila melanogaster (Fruit fly).
   Q18325           UNC-103 PROTEIN - Caenorhabditis elegans.
   O18965           EAG CHANNEL - Bos taurus (Bovine).
   O18966           EAG CHANNEL - Bos taurus (Bovine).
   O76035           POTASSIUM CHANNEL H-EAG - Homo sapiens (Human).
   O95259           VOLTAGE-GATED POTASSIUM CHANNEL EAGB - Homo sapiens (Human).
   Q60603           LONG (ELECTOCARDIOGRAPHIC) QT SYNDROME 2 (POTASSIUM CHANNEL 
   Q63472           POTASSIUM CHANNEL SUBUNIT - Rattus norvegicus (Rat).
   O88877           POTASSIUM CHANNEL - Rattus norvegicus (Rat).
   Q9VXZ6           EAG PROTEIN - Drosophila melanogaster (Fruit fly).
   CIKE_DROME       POTASSIUM CHANNEL PROTEIN EAG - Drosophila melanogaster (Fru
   Q9QXT2           POTASIUM CHANNEL EAG2 - Rattus norvegicus (Rat).
   Q9V899           ELK PROTEIN - Drosophila melanogaster (Fruit fly).
   Q23974           PUTATIVE POTASSIUM CHANNEL SUBUNIT (EAG-LIKE K[+] CHANNEL PR
   Q9R1T9           BEC2 - Rattus norvegicus (Rat).
   O89048           ELK CHANNEL 1 - Rattus norvegicus (Rat).
   Q9UQ05           BEC2 - Homo sapiens (Human).
   O89047           ELK CHANNEL 2 (POTASSIUM CHANNEL) - Rattus norvegicus (Rat).
   Q9UQ06           BEC1 - Homo sapiens (Human).
   Q9WVJ0           ETHER-A-GO-GO-LIKE POTASSIUM CHANNEL - Mus musculus (Mouse).
   O44164           HYPOTHETICAL 105.5 KDA PROTEIN F16B3.1 IN CHROMOSOME IV - Ca
   Q9XYX7           EAG K+ CHANNEL EGL-2 - Caenorhabditis elegans.

SCAN HISTORY SPTR39_14f 3 50 NSINGLE INITIAL MOTIF SETS EAGCHANLFMLY1 Length of motif = 10 Motif number = 1 EAG/ELK/ERG potassium channel family motif I - 1 PCODE ST INT HYCAFKAIWD CIKE_DROME 231 231 HYCVFKTTWD O76035 212 212 HYCVFKTTWD O95259 212 212 HYGVFKGIWD Q23974 262 262 HFSTFKAGWD O88877 216 216 HCGALRATWD O89047 219 219 HYSPFKAVWD O54852 402 402 HYSPFKAVWD O54853 251 251 HYSPFKAVWD O02497 315 315 EAGCHANLFMLY2 Length of motif = 8 Motif number = 2 EAG/ELK/ERG potassium channel family motif II - 1 PCODE ST INT YTAIMVPY CIKE_DROME 249 8 YTAILVPY O76035 230 8 YTAILVPY O95259 230 8 YVALMVPY Q23974 280 8 YVAVTVPY O88877 234 8 YVAVTVPY O89047 237 8 YTAIFTPY O54852 420 8 YTAVFTPY O54853 269 8 YTAIFTPY O02497 333 8 EAGCHANLFMLY3 Length of motif = 11 Motif number = 3 Ether-a-go-go (eag)-like potassium channel familymotif III - 1 PCODE ST INT DSIVDVIFFID CIKE_DROME 274 17 DSIVDVIFLVD O76035 254 16 DSIVDVIFLVD O95259 254 16 DVIVEALFIVD Q23974 302 14 DIAVEILFIID O88877 261 19 DLAVEVLFILD O89047 265 20 DLIVDIMFIID O54852 455 27 DLIVDIMFVVD O54853 304 27 DLIVDVTFIVD O02497 368 27 EAGCHANLFMLY4 Length of motif = 10 Motif number = 4 EAG/ELK/ERG potassium channel family motif IV - 1 PCODE ST INT IVLNFHTTFV CIKE_DROME 285 0 IVLNFHTTFV O76035 265 0 IVLNFHTTFV O95259 265 0 ILLNFRTTFV Q23974 313 0 IILNFRTTYV O88877 272 0 IVLNFRTTFV O89047 276 0 ILINFRTTYV O54852 466 0 IVINFRTTYV O54853 315 0 IIINFRTTFV O02497 379 0 EAGCHANLFMLY5 Length of motif = 11 Motif number = 5 EAG/ELK/ERG potassium channel family motif V - 1 PCODE ST INT LVAHWLACIWY CIKE_DROME 381 86 LAAHWMACIWY O76035 361 86 LAAHWMACIWY O95259 388 113 LAAHWLACIWY Q23974 408 85 LLAHWMACIWY O88877 365 83 LLAHWVACVWF O89047 369 83 LIAHWLACIWY O54852 561 85 LIAHWLACIWY O54853 410 85 LIAHWLACIWY O02497 474 85 EAGCHANLFMLY6 Length of motif = 18 Motif number = 6 EAG/ELK/ERG potassium channel family motif VI - 1 PCODE ST INT YVTALYFTMTCMTSVGFG CIKE_DROME 440 48 YISSLYFTMTSLTSVGFG O76035 423 51 YISSLYFTMTSLTSVGFG O95259 450 51 YSTALYFTFTSLTSVGFG Q23974 456 37 YIAALYFTLSSLTSVGFG O88877 421 45 YITSLYFALSSLTSVGFG O89047 455 75 YVTALYFTFSSLTSVGFG O54852 614 42 YVTALYFTFSSLTSVGFG O54853 463 42 YITALYFTFTSLTSVGFG O02497 526 41 EAGCHANLFMLY7 Length of motif = 12 Motif number = 7 EAG/ELK/ERG potassium channel family motif VII - 1 PCODE ST INT EKVFTICMMIIA CIKE_DROME 466 8 EKIFAVAIMMIG O76035 449 8 EKIFAVAIMMIG O95259 476 8 EKVFTIIMMLIG Q23974 482 8 EKIFSICTMLIG O88877 447 8 EKIFSICTMLIG O89047 481 8 EKIFSICVMLIG O54852 640 8 EKVFSICVMLIG O54853 489 8 EKAFTICVMLVG O02497 552 8 EAGCHANLFMLY8 Length of motif = 10 Motif number = 8 EAG/ELK/ERG potassium channel family motif VIII - 1 PCODE ST INT IFGHVTTIIQ CIKE_DROME 484 6 IFGNVTTIFQ O76035 467 6 IFGNVTTIFQ O95259 494 6 VFGNVTAIIQ Q23974 500 6 VFGNVTAIIQ O88877 465 6 VFGNVTAIIQ O89047 499 6 IFGNVSAIIQ O54852 658 6 IFGNVSAIIQ O54853 507 6 IFGNVSAIIQ O02497 570 6 EAGCHANLFMLY9 Length of motif = 8 Motif number = 9 EAG/ELK/ERG potassium channel family motif IX - 1 PCODE ST INT WAMTKGLD CIKE_DROME 534 40 WSMSRGID O76035 517 40 WSMSRGID O95259 544 40 WSLSHGID Q23974 550 40 WSVNNGID O88877 515 40 WAVNNGID O89047 549 40 WTYTNGID O54852 708 40 WSYTNGID O54853 557 40 WTYTNGID O02497 620 40 EAGCHANLFMLY10 Length of motif = 9 Motif number = 10 EAG/ELK/ERG potassium channel family motif X - 1 PCODE ST INT VRALTYCDL CIKE_DROME 651 109 VRALTYCDL O76035 634 109 VRALTYCDL O95259 661 109 IKALTYCDL Q23974 684 126 VKALTYCDL O88877 631 108 VKGLTYCVL O89047 665 108 VRALTYCDL O54852 825 109 VRALTYCDL O54853 674 109 VRALTYCDI O02497 736 108 FINAL MOTIF SETS EAGCHANLFMLY1 Length of motif = 10 Motif number = 1 EAG/ELK/ERG potassium channel family motif I - 3 PCODE ST INT HYSPFKAVWD HERG_HUMAN 402 402 HYSPFKAVWD O35219 404 404 HYSPFKAVWD O35220 62 62 HYSPFKAVWD O35221 404 404 HYSPFKAVWD O35989 62 62 HYSPFKAVWD O19119 387 387 HYSPFKAVWD O08962 404 404 HYSPFKAVWD O54853 251 251 HYSPFKAVWD Q9TSZ3 401 401 HYSPFKAVWD O54852 402 402 HYSPFKAVWD O02497 315 315 HYSPFKAVWD Q18325 75 75 HYCVFKTTWD O18965 212 212 HYCVFKTTWD O18966 212 212 HYCVFKTTWD O76035 212 212 HYCVFKTTWD O95259 212 212 HYCVFKTTWD Q60603 212 212 HYCVFKTTWD Q63472 212 212 HFSTFKAGWD O88877 216 216 HYCAFKAIWD CIKE_DROME 231 231 HYCAFKAIWD Q9VXZ6 231 231 HYCAFKTTWD Q9QXT2 209 209 HYGVFKGIWD Q23974 262 262 HYGVFKGIWD Q9V899 289 289 HYSIPKAVWD O89048 222 222 HYSIPKAVWD Q9R1T9 222 222 HYSVSKAIWD Q9UQ05 221 221 HCGALRATWD O89047 219 219 HCGALRATWD Q9UQ06 219 219 HCGALRATWD Q9WVJ0 219 219 HYSSFKTIWD O44164 190 190 HYSSFKTIWD Q9XYX7 211 211 EAGCHANLFMLY2 Length of motif = 8 Motif number = 2 EAG/ELK/ERG potassium channel family motif II - 3 PCODE ST INT YTAVFTPY HERG_HUMAN 420 8 YTAVFTPY O35219 422 8 YTAVFTPY O35220 80 8 YTAVFTPY O35221 422 8 YTAVFTPY O35989 80 8 YTAVFTPY O19119 405 8 YTAVFTPY O08962 422 8 YTAVFTPY O54853 269 8 YTAVFTPY Q9TSZ3 419 8 YTAIFTPY O54852 420 8 YTAIFTPY O02497 333 8 YTAVFTPY Q18325 93 8 YTAILVPY O18965 230 8 YTAILVPY O18966 230 8 YTAILVPY O76035 230 8 YTAILVPY O95259 230 8 YTAILVPY Q60603 230 8 YTAILVPY Q63472 230 8 YVAVTVPY O88877 234 8 YTAIMVPY CIKE_DROME 249 8 YTAIMVPY Q9VXZ6 249 8 YTAIMVPY Q9QXT2 227 8 YVALMVPY Q23974 280 8 YVALMVPY Q9V899 307 8 YVAVTVPY O89048 240 8 YVAVTVPY Q9R1T9 240 8 YVAVTVPY Q9UQ05 239 8 YVAVTVPY O89047 237 8 YVAVTVPY Q9UQ06 237 8 YVAVTVPY Q9WVJ0 237 8 YTAFMVPF O44164 208 8 YTAFMVPF Q9XYX7 229 8 EAGCHANLFMLY3 Length of motif = 11 Motif number = 3 Ether-a-go-go (eag)-like potassium channel family III - 3 PCODE ST INT DLIVDIMFIVD HERG_HUMAN 456 28 DLIVDIMFIVD O35219 458 28 DLIVDIMFIVD O35220 116 28 DLIVDIMFIVD O35221 458 28 DLIVDIMFIVD O35989 116 28 DLIVDIMFIVD O19119 441 28 DLLVDIMFIVD O08962 458 28 DLIVDIMFVVD O54853 304 27 DFIVDIMFIVD Q9TSZ3 455 28 DLIVDIMFIID O54852 455 27 DLIVDVTFIVD O02497 368 27 DLIVDIMFIVD Q18325 126 25 DSIVDVIFLVD O18965 254 16 DSIVDVIFLVD O18966 254 16 DSIVDVIFLVD O76035 254 16 DSIVDVIFLVD O95259 254 16 DSIVDVIFLVD Q60603 254 16 DSIVDVIFLVD Q63472 254 16 DIAVEILFIID O88877 261 19 DSIVDVIFFID CIKE_DROME 274 17 DSIVDVIFFID Q9VXZ6 274 17 DSVVDVIFLVD Q9QXT2 251 16 DVIVEALFIVD Q23974 302 14 DVIVEALFIVD Q9V899 329 14 DIAVEMLFILD O89048 268 20 DIAVEMLFILD Q9R1T9 268 20 DIAVEMLFILD Q9UQ05 267 20 DLAVEVLFILD O89047 265 20 DLAVEVLFILD Q9UQ06 265 20 DLAVEVLFILD Q9WVJ0 265 20 DSIVDVIFFAD O44164 238 22 DSIVDVIFFAD Q9XYX7 267 30 EAGCHANLFMLY4 Length of motif = 10 Motif number = 4 EAG/ELK/ERG potassium channel family motif IV - 3 PCODE ST INT ILINFRTTYV HERG_HUMAN 467 0 ILINFRTTYV O35219 469 0 ILINFRTTYV O35220 127 0 ILINFRTTYV O35221 469 0 ILINFRTTYV O35989 127 0 ILINFRTTYV O19119 452 0 ILINFRTTYV O08962 469 0 IVINFRTTYV O54853 315 0 ILINFRTTYV Q9TSZ3 466 0 ILINFRTTYV O54852 466 0 IIINFRTTFV O02497 379 0 IIINFRTTYV Q18325 137 0 IVLNFHTTFV O18965 265 0 IVLNFHTTFV O18966 265 0 IVLNFHTTFV O76035 265 0 IVLNFHTTFV O95259 265 0 IVLNFHTTFV Q60603 265 0 IVLNFHTTFV Q63472 265 0 IILNFRTTYV O88877 272 0 IVLNFHTTFV CIKE_DROME 285 0 IVLNFHTTFV Q9VXZ6 285 0 IVLNFHTTFV Q9QXT2 262 0 ILLNFRTTFV Q23974 313 0 ILLNFRTTFV Q9V899 340 0 IILNFRTTYV O89048 279 0 IILNFRTTYV Q9R1T9 279 0 IILNFRTTYV Q9UQ05 278 0 IVLNFRTTFV O89047 276 0 IVLNFRTTFV Q9UQ06 276 0 IVLNFRTTFV Q9WVJ0 276 0 ILLNFHTTFV O44164 249 0 ILLNFHTTFV Q9XYX7 278 0 EAGCHANLFMLY5 Length of motif = 11 Motif number = 5 EAG/ELK/ERG potassium channel family motif V - 3 PCODE ST INT LIAHWLACIWY HERG_HUMAN 559 82 LIAHWLACIWY O35219 561 82 LIAHWLACIWY O35220 219 82 LIAHWLACIWY O35221 561 82 LIAHWLACIWY O35989 219 82 LIAHWLACIWY O19119 544 82 LIAHWLACIWY O08962 561 82 LIAHWLACIWY O54853 410 85 LIAHWLACIWY Q9TSZ3 558 82 LIAHWLACIWY O54852 561 85 LIAHWLACIWY O02497 474 85 LIAHWLACIWY Q18325 235 88 LAAHWMACIWY O18965 361 86 LAAHWMACIWY O18966 388 113 LAAHWMACIWY O76035 361 86 LAAHWMACIWY O95259 388 113 LAAHWMACIWY Q60603 388 113 LAAHWMACIWY Q63472 361 86 LLAHWMACIWY O88877 365 83 LVAHWLACIWY CIKE_DROME 381 86 LVAHWLACIWY Q9VXZ6 381 86 LVAHWLACIWY Q9QXT2 358 86 LAAHWLACIWY Q23974 408 85 LAAHWLACIWY Q9V899 435 85 LLAHWMACVWY O89048 372 83 LLAHWMACVWY Q9R1T9 372 83 LLAHWMACIWY Q9UQ05 371 83 LLAHWVACVWF O89047 369 83 LLAHWVACVWF Q9UQ06 369 83 LLAHWVACVWF Q9WVJ0 369 83 IVAHWLACVWF O44164 345 86 IVAHWLACVWF Q9XYX7 374 86 EAGCHANLFMLY6 Length of motif = 18 Motif number = 6 EAG/ELK/ERG potassium channel family motif VI - 3 PCODE ST INT YVTALYFTFSSLTSVGFG HERG_HUMAN 611 41 YVTALYFTFSSLTSVGFG O35219 613 41 YVTALYFTFSSLTSVGFG O35220 271 41 YVTALYFTFSSLTSVGFG O35221 613 41 YVTALYFTFSSLTSVGFG O35989 271 41 YVTGLYFTFSSLTSVGFG O19119 596 41 YVTALYFTFSSLTSVGFG O08962 613 41 YVTALYFTFSSLTSVGFG O54853 463 42 YVTALYFTFSSLTSVGFG Q9TSZ3 610 41 YVTALYFTFSSLTSVGFG O54852 614 42 YITALYFTFTSLTSVGFG O02497 526 41 YVTSLYFTLSTITSIGFG Q18325 289 43 YISSLYFTMTSLTSVGFG O18965 423 51 YISSLYFTMTSLTSVGFG O18966 450 51 YISSLYFTMTSLTSVGFG O76035 423 51 YISSLYFTMTSLTSVGFG O95259 450 51 YISSLYFTMTSLTSVGFG Q60603 450 51 YISSLYFTMTSLTSVGFG Q63472 423 51 YIAALYFTLSSLTSVGFG O88877 421 45 YVTALYFTMTCMTSVGFG CIKE_DROME 440 48 YVTALYFTMTCMTSVGFG Q9VXZ6 440 48 YVSSLYFTMTSLTTIGFG Q9QXT2 419 50 YSTALYFTFTSLTSVGFG Q23974 456 37 YSTALYFTFTSLTSVGFG Q9V899 483 37 YIAALYFTLSSLTSVGFG O89048 427 44 YIAALYFTLSSLTSVGFG Q9R1T9 427 44 YIAALYFTLSSLTSVGFG Q9UQ05 426 44 YITSLYFALSSLTSVGFG O89047 455 75 YITSLYFALSSLTSVGFG Q9UQ06 452 72 YITSLYFALSSLTSVGFG Q9WVJ0 455 75 YISSLYYTMSCMSTVGFG O44164 407 51 YISSLYYTMSCMSTVGFG Q9XYX7 436 51 EAGCHANLFMLY7 Length of motif = 12 Motif number = 7 EAG/ELK/ERG potassium channel family motif VII - 3 PCODE ST INT EKIFSICVMLIG HERG_HUMAN 637 8 EKIFSICVMLIG O35219 639 8 EKIFSICVMLIG O35220 297 8 EKIFSICVMLIG O35221 639 8 EKIFSICVMLIG O35989 297 8 EKIFSICVMLIG O19119 622 8 EKIFSICVMLIG O08962 639 8 EKVFSICVMLIG O54853 489 8 EKIFSICVMLIG Q9TSZ3 636 8 EKIFSICVMLIG O54852 640 8 EKAFTICVMLVG O02497 552 8 EKIFTIIMMILG Q18325 315 8 EKIFAVAIMMIG O18965 449 8 EKIFAVAIMMIG O18966 476 8 EKIFAVAIMMIG O76035 449 8 EKIFAVAIMMIG O95259 476 8 EKIFAVAIMMIG Q60603 476 8 EKIFAVAIMMIG Q63472 449 8 EKIFSICTMLIG O88877 447 8 EKVFTICMMIIA CIKE_DROME 466 8 EKVFTICMMIIA Q9VXZ6 466 8 EKMFSVAMMMVG Q9QXT2 445 8 EKVFTIIMMLIG Q23974 482 8 EKVFTIIMMLIG Q9V899 509 8 EKIFSICTMLIG O89048 453 8 EKIFSICTMLIG Q9R1T9 453 8 EKIFSICTMLIG Q9UQ05 452 8 EKIFSICTMLIG O89047 481 8 EKIFSICTMLIG Q9UQ06 478 8 EKIFSICTMLIG Q9WVJ0 481 8 EKIFGVCMMIIS O44164 433 8 EKIFGVCMMIIS Q9XYX7 462 8 EAGCHANLFMLY8 Length of motif = 10 Motif number = 8 EAG/ELK/ERG potassium channel family motif VIII - 3 PCODE ST INT IFGNVSAIIQ HERG_HUMAN 655 6 IFGNVSAIIQ O35219 657 6 IFGNVSAIIQ O35220 315 6 IFGNVSAIIQ O35221 657 6 IFGNVSAIIQ O35989 315 6 IFGNVSAIIQ O19119 640 6 IFGNVSAIIQ O08962 657 6 IFGNVSAIIQ O54853 507 6 IFGNVSAIIQ Q9TSZ3 654 6 IFGNVSAIIQ O54852 658 6 IFGNVSAIIQ O02497 570 6 VFGNVSAIIQ Q18325 333 6 IFGNVTTIFQ O18965 467 6 IFGNVTTIFQ O18966 494 6 IFGNVTTIFQ O76035 467 6 IFGNVTTIFQ O95259 494 6 IFGNVTTIFQ Q60603 494 6 IFGNVTTIFQ Q63472 467 6 VFGNVTAIIQ O88877 465 6 IFGHVTTIIQ CIKE_DROME 484 6 IFGHVTTIIQ Q9VXZ6 484 6 IFGNVTTIFQ Q9QXT2 463 6 VFGNVTAIIQ Q23974 500 6 VFGNVTAIIQ Q9V899 527 6 VFGNVTAIIQ O89048 471 6 VFGNVTAIIQ Q9R1T9 471 6 VFGNVTAIIQ Q9UQ05 470 6 VFGNVTAIIQ O89047 499 6 VFGNVTAIIQ Q9UQ06 496 6 VFGNVTAIIQ Q9WVJ0 499 6 IFGHMTTIIQ O44164 451 6 IFGHMTTIIQ Q9XYX7 480 6 EAGCHANLFMLY9 Length of motif = 8 Motif number = 9 EAG/ELK/ERG potassium channel family motif IX - 3 PCODE ST INT WSYTNGID HERG_HUMAN 705 40 WSYTNGID O35219 707 40 WSYTNGID O35220 365 40 WSYTNGID O35221 707 40 WSYTNGID O35989 365 40 WSYTNGID O19119 690 40 WSYTNGID O08962 707 40 WSYTNGID O54853 557 40 WSYTNGID Q9TSZ3 704 40 WTYTNGID O54852 708 40 WTYTNGID O02497 620 40 WSYTNGID Q18325 383 40 WSMSRGID O18965 517 40 WSMSRGID O18966 544 40 WSMSRGID O76035 517 40 WSMSRGID O95259 544 40 WSMSRGID Q60603 544 40 WSMSRGID Q63472 517 40 WSVNNGID O88877 515 40 WAMTKGLD CIKE_DROME 534 40 WAMTKGLD Q9VXZ6 534 40 WSMSKGID Q9QXT2 513 40 WSLSHGID Q23974 550 40 WSLSHGID Q9V899 577 40 WAVNSGID O89048 521 40 WAVNSGID Q9R1T9 521 40 WAVNSGID Q9UQ05 520 40 WAVNNGID O89047 549 40 WAVNNGID Q9UQ06 546 40 WAVNNGID Q9WVJ0 549 40 WAMTKGID O44164 501 40 WAMTKGID Q9XYX7 530 40 EAGCHANLFMLY10 Length of motif = 9 Motif number = 10 EAG/ELK/ERG potassium channel family motif X - 3 PCODE ST INT VRALTYCDL HERG_HUMAN 822 109 VRALTYCDL O35219 824 109 VRALTYCDL O35220 482 109 VRALTYCDL O35221 824 109 VRALTYCDL O35989 482 109 VRALTYCDL O19119 807 109 VRALTYCDL O08962 824 109 VRALTYCDL O54853 674 109 VRALTYCDL Q9TSZ3 821 109 VRALTYCDL O54852 825 109 VRALTYCDI O02497 736 108 VRALTYCDL Q18325 501 110 VRALTYCDL O18965 634 109 VRALTYCDL O18966 661 109 VRALTYCDL O76035 634 109 VRALTYCDL O95259 661 109 VRALTYCDL Q60603 661 109 VRALTYCDL Q63472 634 109 VKALTYCDL O88877 631 108 VRALTYCDL CIKE_DROME 651 109 VRALTYCDL Q9VXZ6 651 109 VRALTYCDL Q9QXT2 630 109 IKALTYCDL Q23974 684 126 IKALTYCDL Q9V899 711 126 VKALTYCGL O89048 645 116 VKALTYCGL Q9R1T9 645 116 VKALTYCGL Q9UQ05 646 118 VKGLTYCVL O89047 665 108 VKGLTYCVL Q9UQ06 662 108 VKGLTYCVL Q9WVJ0 665 108 VRALTYSDL O44164 619 110 VRALTYSDL Q9XYX7 648 110

User query: Display/Full Code "EAGCHANLFMLY"